Dee Snider graduated Baldwin Senior High School, Baldwin, New York (Long Island) in 1973.

He took on Tipper Gore and her "watchdog" group, the Parents Music Resource Center (PMRC), when she tried to get his band Twisted Sister's album banned, and he spoke in favor of musicians rights included in the First Amendment. He actively campaigned for Arnold Schwarzenegger in that actor's campaign for the California governor (even going as far as to sing his song "We're Not Gonna Take It" at rallies for both men).

Dee Snider shares a birthday with Poison lead singer Bret Michaels.

Dee Snider has three sons, Jesse Blaze Snider, Shane Snider and Cody Snider, plus a daughter, Cheyenne Snider.