The title of their debut album, Amongst The Catacombs Of Nephren-Ka, is a direct quote from H.P. Lovecraft's short story "The Outsider".

On the album In Their Darkened Shrines, the two main melodies of "Unas Slayer Of The Gods" are a tribute to "Gothic Stone/The Well of Souls" by Candlemass, from their doom metal album Nightfall.

Much of the lyrical content is based on Karl Sanders' interest in Egyptology and other ancient Middle Eastern cultures, such as Mesopotamia. Lengthy sleeve notes are included with the albums 'Black Seeds of Vengeance', 'In Their Darkened Shrines' and 'Annihilation of the Wicked', explaining the inspiration or source for the lyrics of each song. Some songs, moreover, are based on the works of H. P. Lovecraft, whose writing has strongly influenced the style and grammatical peculiarities of Nile's lyrics.

Karl Sanders's favorite computer game is Call of Duty.

Many people mistake members of Nile as being Egyptian or having ancestors of that nationality. The funny thing is none of them are Egyptian in any way or form, but the group has a huge interest in the Egyptian studies (especially Karl Sanders). For the most part, they're all American-born and of white descent (except for their current drummer, George Kollias who is Greek and their previous drummer, Tony Laureano who is originally from Puerto Rico).